Knowledge transmission near the young adults in situation of handicap is part from now on of the managerial concerns of the companies. It holds an important place in the relations between the various generations of employees since the transmission became a major stake of integration. Its experimental methods (relation of assistance, accompaniment, guardianship, coaching, visit of site) are numerous and fall under a marked logic of professional insertion. Up to what point does the intergenerational transmission of the knowledge support the training of the young adults in situation of handicap confronted with differentiated cultures of training? Two competitor models of transmission can be highlighted and discussed at the glance of the professionalization of the referents which contribute to insertion in the youth employment handicapped.